Not known Factual Statements About Akorn Promethazine with codeine syrup
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Labor or Shipping Opioids cross the placenta and should deliver respiratory depression and psycho-physiologic effects in neonates. An opioid antagonist, including naloxone, must be obtainable for reversal of opioid-induced respiratory melancholy from the neonate.
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Allergies to Ingredients. People who find themselves allergic to any of the next shouldn't consider promethazine/codeine.
“Codeine linctus is an efficient drugs for long-lasting dry cough, but as it really is an opioid, its misuse and abuse may have main well being penalties.”
Daily life-threatening respiratory depression and death have occurred in small children who gained codeine. Codeine is matter to variability in metabolism centered on CYP2D6 genotype (explained under), which can cause an increased exposure on the Energetic metabolite morphine. Primarily based upon post-advertising stories, children youthful than twelve years old appear to be more prone to the respiratory depressant results of codeine, especially if there are actually possibility factors for respiratory depression.
Promethazine hydrochloride was not mutagenic within the in vitro bacterial reverse mutation assay or clastogenic during the in vitro Chinese hamster ovary (CHO) mobile chromosomal aberration assay.
與其它鴉片類藥物一樣，可待因的其中一個潛在的嚴重不良反應是壓抑呼吸，通常與服用過量有關，可引致死亡。
Tend not to take any benzodiazepines or medicines that may cause drowsiness or sleepiness all through treatment method with Promethazine Hydrochloride and Codeine Phosphate Oral Solution. Question your read more Health care provider for a summary of these medicines if You aren't confident.
The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals below 6 a long time of age, due to the fact The mixture may possibly lead to more info deadly respiratory melancholy In this particular age populace (see WARNINGS Box Warning and Use in Pediatric Patients).
Sedating drugs could induce confusion and in excess of-sedation check here during the elderly; elderly individuals usually really should be begun on minimal doses of Promethazine Hydrochloride and check here Codeine Phosphate Syrup and noticed carefully.
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Breastfeeding. Will not consider promethazine/codeine when you are breastfeeding. Promethazine/codeine can go into breast milk. Notify your healthcare supplier For anyone who is breastfeeding or intend to breastfeed.
Responses towards check here the consultation discovered the force pharmacists have been beneath to supply the drugs to All those suffering from addiction.
This drugs may possibly incorporate aspartame. For those who have phenylketonuria (PKU) or almost every other problem that needs you to restrict your ingestion of aspartame (or phenylalanine), talk to your medical doctor or pharmacist regarding the Protected use of this drugs.